SMB processes can be developed in a few weeks and the process is easily scalable; in most cases, scale-up from gram to multi-ton quantities can be achieved in less than 6 months. This unit operation, approved by the US FDA for the production of certain drugs, provides high purity material with high recovery at a competitive price as compared to traditional purification methods. Typical applications are:
AFC provides support for all phases of drug development with emphasis on commercial scale production of intermediates and APIs. Our services include SMB screening, methods development, proof-of-concept demonstration, and production of gram to multi-ton quantities of fine chemicals.